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Weekly totals of 250-1000mg weekly are frequently used, and sometimes more for the highly advanced athlete. Due to the relatively long half life of enanthate (4-5 days), injections are usually administered twice per week. This will allow stable blood levels to be maintained. When the level of steroid tapers down, a new injection is made, keeping everything fairly level. This is unlike sustanon, which requires more frequent injections for the same effect. For a first cycle, 500mg alone of testosterone enanthate, shot two times weekly (Monday and Thursday for example), for 10 weeks along with standard post cycle therapy would be very sufficient for good gains.
Side effects such as water retention usually occur when using testosterone enanthate. Gyno, increased rate of hair growth, back acne, increased blood pressure, and aggressiveness, both in the gym and out, are possible when using enanthate. The liver is accustomed to processing testosterone, so liver toxicity is normally not a concern except at extremely high doses.